Decline of gastric cancer mortality in common variable immunodeficiency in the years 2018-2022

In patients with Common Variable Immunodeficiency malignancy has been reported as the leading cause of death in adults, with a high risk of B-cell lymphomas and gastric cancer. We conducted a five-year prospective study aiming to update the incidence and mortality of gastric cancer and the incidence of gastric precancerous lesions in 512 CVID patients who underwent a total of 400 upper gastrointestinal endoscopies.