The Clinical Course of SARS-CoV-2 Infection in Patients With Autoimmune Neutropenia: A Retrospective Case Series Study

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Rotulo GA, Ceglie G, Candino A, Merola A, Profeti E, Giancotta C, Mercadante S, Santilli V, Cotugno N, Palma P, Palumbo G, Finocchi A.

Severe acute respiratory syndrome coronavirus 2 infection in children with autoimmune neutropenia may be a cause for concern. In this retrospective study, none of the 24 autoimmune neutropenia cases manifested severe coronavirus disease 2019. We found a significant improvement in neutrophils and a reduction in lymphocytes at post-infection follow-up compared with the median of previous values. We speculate that this paradoxical effect may be due to postinfection immunological phenomena.

Pediatr Infect Dis J. 2023

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